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Related Concept Videos

Clinical Trials01:16

Clinical Trials

10.1K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.1K
Clinical Trials: Overview01:11

Clinical Trials: Overview

4.5K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.5K

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Related Experiment Video

Updated: Jan 7, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
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Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

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Trends in Interventional Clinical Trials Within Plastic Surgery.

Narainsai K Reddy1, Jason Zhang, Sophia G Allison

  • 1Division of Plastic Surgery, Ann and Robert H. Lurie Children's Hospital, Chicago, IL.

The Journal of Craniofacial Surgery
|December 30, 2025
PubMed
Summary
This summary is machine-generated.

Clinical trials in craniofacial surgery represent a small fraction of plastic surgery research. These trials, often funded by academic institutions, require more industry support to advance care for craniofacial conditions.

Keywords:
Craniofacial surgeryinterventional clinical trialsplastic surgeryplastic surgery subspecialties

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Area of Science:

  • Plastic Surgery
  • Craniofacial Surgery
  • Clinical Trials Research

Background:

  • Prospective clinical trials in plastic surgery are underrepresented in craniofacial surgery.
  • Understanding current research is crucial for developing Level I studies in plastic surgery subspecialties.

Purpose of the Study:

  • To analyze the landscape of clinical trials in plastic surgery and its subspecialties.
  • To identify trends in funding, sponsorship, and study design within craniofacial surgery trials.

Main Methods:

  • Data collected from ClinicalTrials.gov using specific search terms for plastic surgery and subspecialties.
  • Analysis of variables including country, sponsor type, intervention, study phase, and primary purpose.
  • Comparison of craniofacial surgery trials with other plastic surgery subspecialties.

Main Results:

  • 44 craniofacial surgery trials identified out of 257 total plastic surgery trials.
  • Craniofacial trials predominantly funded by academic institutions/hospitals and foundations, with limited industry funding.
  • Hand surgery (352) and breast reconstruction (136) had the highest number of trials among subspecialties.

Conclusions:

  • Craniofacial surgery trials constitute a minor portion of plastic surgery clinical trials.
  • Academic institutions are the primary funders of craniofacial trials, unlike industry-funded microsurgery and aesthetic plastic surgery trials.
  • Enhanced focus on prospective craniofacial trials is essential for improving patient care globally.