Related Experiment Video
Updated: Jan 7, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Interrelationships between childhood trauma, alexithymia, and depressive symptoms: A network analysis and replication
Qing-Ying Ye1, Si-Yu Zhang2, Xing-Lin He1
1Institute of Brain Science and Department of Physiology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Background:
Childhood trauma has been found to increase the risk of developing alexithymia and depressive symptoms. However, the complex interplay between childhood trauma, alexithymia, and depressive symptoms remains unclear.
Objective:
To understand how different facets of childhood trauma, alexithymia across positive and negative emotions, and depressive symptoms interact with each other, this study adopted the network analysis approaches to examine this complex relationship.
Participants And Setting:
An initial sample of 2918 Chinese college students completed a set of psychometric questionnaires measuring childhood trauma, alexithymia and depressive symptoms. Another independent sample (n = 858) was used to investigate the replicability of our results.
Methods:
Undirected networks were estimated to explore the most relevant connections between the above variables. Bayesian network analysis was further used to explore the potential causal directions between the variables.
Results:
Findings from the initial dataset showed that childhood trauma was positively correlated with both alexithymia and depressive symptoms in the undirected networks. Physical abuse was the most central node. The Bayesian network analysis indicated that externally orientated thinking and depressed mood may be key drivers for activating other symptoms. Physical abuse might affect suicide ideation through difficulties in describing negative emotions. The replication dataset showed similar network structures as the initial dataset.
Conclusions:
The findings suggest that childhood trauma, especially physical abuse, plays an important role in developing later depressive symptoms via valenced components of alexithymia. This study clarifies how early adversities link to depressive symptoms through emotional functioning and informs clinical interventions targeting influential symptoms in trauma-exposed populations.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Cognitive Development During Adolescence
Relationship with Parents: Attachment
Theory of Romantic Attachment in Adulthood
Depressive Disorders: MDD and Dysthymia
Psychological and Sociocultural Causes of Schizophrenia

