Search

Search

Home
...
Research Domains Biomedical and Clinical Sciences Paediatrics Infant and child health
CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment

CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment

Jeremy Willekens ¹, Sameera Ramjan ², Stephen A Sands ^2,3, Yongkyu Park ⁴, Nirajan K C ⁴, Melissa A Burns ⁵, Jennifer J G Welch ⁶, Justine Kahn ⁷, Kara M Kelly ⁸, Thai-Hoa Tran ⁹, Bruno Michon ¹⁰, Lisa Gennarini ¹¹, Andrew Place ⁵, Lewis B Silverman ⁵, Peter D Cole ^4,12

Jeremy Willekens ¹, Sameera Ramjan ², Stephen A Sands ^2,3

¹Rutgers Cancer Institute, Division of Pediatric Hematology/Oncology, New Brunswick, NJ, USA. jw1327@cinj.rutgers.edu.
²Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
³Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
⁴Rutgers Cancer Institute, Division of Pediatric Hematology/Oncology, New Brunswick, NJ, USA.
⁵Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Harvard Medical School, Boston, MA, USA.
⁶Division of Pediatric Hematology/Oncology, Alpert School of Medicine, Brown University, Providence, RI, USA.
⁷Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Columbia University Medical Center, New York, NY, USA.
⁸Department of Pediatrics, Roswell Park Comprehensive Cancer Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
⁹Division of Pediatric Hematology Oncology, Charles-Bruneau Cancer Center, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
¹⁰Centre Hospitalier Universitaire de Quebec, Quebec City, QC, Canada.
¹¹Children's Hospital at Montefiore, Bronx, NY, USA.
¹²Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

⁰Rutgers Cancer Institute, Division of Pediatric Hematology/Oncology, New Brunswick, NJ, USA. jw1327@cinj.rutgers.edu.

Molecular Medicine (Cambridge, Mass.) +

|

December 30, 2025

Related Experiment Videos

These videos have been matched automatically. Contact us if they are not relevant.

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

See all related videos

Summary

No abstract available on PubMed

Keywords:

Biomarker Cerebrospinal fluid Chemobrain Chemotherapy-Related Cognitive Impairment Glycerophospholipid metabolism Metabolomics Neurocognitive functioning Pediatric Acute Lymphoblastic Leukemia Survivorship

Related Experiment Videos

These videos have been matched automatically. Contact us if they are not relevant.

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

See all related videos

Share

X
Facebook
LinkedIn
YouTube

ABOUT JoVE

Overview
Leadership
Blog
JoVE Help Center

AUTHORS

Publishing Process
Editorial Board
Scope & Policies
Peer Review
FAQ
Submit

LIBRARIANS

Testimonials
Subscriptions
Access
Resources
Library Advisory Board
FAQ

RESEARCH

JoVE Journal
Methods Collections
JoVE Encyclopedia of Experiments
Archive

EDUCATION

JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Faculty Resource Center
Faculty Site

Terms & Conditions of Use
Privacy Policy
Policies