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Lactate-related biomarkers in severe acute pancreatitis: insights from machine learning, molecular dynamics, and

Jifeng Liu1,2, Shuyuan Liu1,2,3, Jingyuan Ma4

  • 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Journal of Biological Engineering
|December 30, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Acute pancreatitisDrug predictionLactate metabolismMachine learningMolecular dynamic simulation

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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