Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Histone Variants at the Centromere02:30

Histone Variants at the Centromere

4.9K
Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
4.9K
Centrioles and Centrosomes01:13

Centrioles and Centrosomes

5.1K
Most animal cells comprise a pair of centrioles together called a centrosome. The cell duplicates its centrosome and contains two centrosomes side-by-side, which begin to move apart during the prophase. As the centrosomes migrate to two different sides of the cell, microtubules start extending from each centrosome toward the other end. The mitotic spindle is composed of the centrosomes and their emerging microtubules.
Near the end of the prophase, also called late prophase or...
5.1K
Centrosome Duplication02:25

Centrosome Duplication

4.8K
The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disability-Informed Graduate-Student Mentors Foster Co-Regulation for Undergraduates in STEM with Learning and Attention Disabilities.

Journal of postsecondary education and disability·2024
Same author

<i>Huperziacrassifolia</i> (Lycopodiaceae), a new species from China based on morphological characters and molecular evidence.

PhytoKeys·2024
Same author

The Possible Earliest Allopolyploidization in Tracheophytes Revealed by Phylotranscriptomics and Morphology of Selaginellaceae.

Molecular biology and evolution·2024
Same author

<i>Primulaweiliei</i> (Primulaceae), a new species from Hubei, Central China.

PhytoKeys·2024
Same author

Stigma and Stigma Resilience: Role of the Undergraduate and the Campus Environment.

OTJR : occupation, participation and health·2024
Same author

The first homosporous lycophyte genome revealed the association between the recent dynamic accumulation of LTR-RTs and genome size variation.

Plant molecular biology·2023

Related Experiment Video

Updated: Jan 7, 2026

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins
05:35

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins

Published on: March 3, 2016

15.6K

CentriVision: An integrated platform for multiscale centromere analysis in plants.

Mei-Fang Lan1, Xi-Yin Wang2, Xian-Chun Zhang3

  • 1Center for Genomics and Bio-computing, School of Life Science, College of Sciences, North China University of Science and Technology, Tangshan 063000, China; State Key Laboratory of Plant Diversity and Specialty Crops and Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; China National Botanical Garden, Beijing 100093, China.

Plant Communications
|December 31, 2025
PubMed
Summary
This summary is machine-generated.

CentriVision, a new bioinformatics platform, analyzes plant centromere DNA repeats and structure. It reveals diverse centromere organizations and evolutionary patterns across species, advancing genome stability research.

Keywords:
CENH3 bindingcentromeremonomer organizationrepeat evolutiontandem repeat

More Related Videos

An Efficient Method for Quantitative, Single-cell Analysis of Chromatin Modification and Nuclear Architecture in Whole-mount Ovules in Arabidopsis
09:33

An Efficient Method for Quantitative, Single-cell Analysis of Chromatin Modification and Nuclear Architecture in Whole-mount Ovules in Arabidopsis

Published on: June 19, 2014

13.5K
A Fast Air-dry Dropping Chromosome Preparation Method Suitable for FISH in Plants
09:08

A Fast Air-dry Dropping Chromosome Preparation Method Suitable for FISH in Plants

Published on: December 16, 2015

13.8K

Related Experiment Videos

Last Updated: Jan 7, 2026

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins
05:35

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins

Published on: March 3, 2016

15.6K
An Efficient Method for Quantitative, Single-cell Analysis of Chromatin Modification and Nuclear Architecture in Whole-mount Ovules in Arabidopsis
09:33

An Efficient Method for Quantitative, Single-cell Analysis of Chromatin Modification and Nuclear Architecture in Whole-mount Ovules in Arabidopsis

Published on: June 19, 2014

13.5K
A Fast Air-dry Dropping Chromosome Preparation Method Suitable for FISH in Plants
09:08

A Fast Air-dry Dropping Chromosome Preparation Method Suitable for FISH in Plants

Published on: December 16, 2015

13.8K

Area of Science:

  • Genomics and Bioinformatics
  • Molecular Biology
  • Plant Science

Background:

  • Centromeres are essential for chromosome segregation and genome stability.
  • Telomere-to-telomere (T2T) assemblies highlight the importance of centromeric regions in genome-wide studies.
  • Understanding centromere structure and evolution is crucial for genome research.

Purpose of the Study:

  • To develop CentriVision, a bioinformatics platform for centromere analysis.
  • To identify candidate centromeres, assess structural similarity, and decompose DNA repeat units.
  • To explore relationships between sequence conservation and functional features, integrating with CENH3 ChIP-seq data.

Main Methods:

  • Development of a modular bioinformatics platform, CentriVision.
  • Utilized tools including editing-distance dotplots, heatmaps, and repeat monomer scanning.
  • Integrated analyses with CENH3 ChIP-seq data for functional insights.

Main Results:

  • CentriVision accurately identified diverse centromere organizational patterns in plants.
  • Arabidopsis thaliana centromeres show conserved repeats potentially representing pre-centromeric sequences.
  • Oryza sativa has two dominant repeat classes, Zea mays evolves a single dominant repeat unit, and Papaver setigerum exhibits a three-layered nested structure.

Conclusions:

  • CentriVision provides a framework to connect repeat evolution, structural variation, and epigenomics.
  • The study reveals species-specific centromere evolutionary trajectories.
  • Findings advance understanding of plant centromere architecture, diversification, and function.