Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

6.6K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standardized Analytical Verification of ctDNA ESR1 Mutation Testing in Metastatic HR+/HER2- Breast Cancer: A European Multicentre Study Using dPCR and NGS-Based Liquid Biopsy.

Molecular diagnosis & therapy·2026
Same author

Renal allograft malakoplakia mimicking malignancy: the value of combined morphological and functional imaging.

Clinical kidney journal·2026
Same author

Urokinase Plasminogen Activator Receptor-Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST).

International journal of cancer·2026
Same author

Milk and honey: how skin changes reveal the deeper dangers of nutritional deficiencies.

Acta clinica Belgica·2026
Same author

A morphomolecular study of 175 'USP6-associated neoplasms': The USP6 fusion partner strongly depends on morphology and location.

Histopathology·2025
Same author

Reply to Taal et al. Comment on "Iasella et al. Close Follow-Up of Patients with Neurofibromatosis Type 1 Reduces the Incidence of Malignant Peripheral Nerve Sheath Tumour. <i>Cancers</i> 2025, <i>17</i>, 1306".

Cancers·2025

Related Experiment Video

Updated: Jan 7, 2026

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
09:43

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts

Published on: August 1, 2025

685

Cellular Angiofibroma of the Prostate.

Fien Janssens1, Celia Perdaens2, Isabelle Vanden Bempt3

  • 1Department of Urology AZ Jan Portaels Vilvoorde and University Hospital Brussels Brussels Belgium.

IJU Case Reports
|December 31, 2025
PubMed
Summary

This case report details a rare instance of cellular angiofibroma, a benign mesenchymal tumor, found in the prostate of an elderly male patient. The diagnosis was confirmed through histopathology and molecular analysis.

Keywords:
cellular angiofibromahistopathologymesenchymal tumorprostateurology

More Related Videos

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

13.7K
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

26.0K

Related Experiment Videos

Last Updated: Jan 7, 2026

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
09:43

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts

Published on: August 1, 2025

685
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

13.7K
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

26.0K

Area of Science:

  • Oncology
  • Urology
  • Pathology

Background:

  • Cellular angiofibroma is a rare, benign mesenchymal tumor typically affecting middle-aged adults.
  • It commonly occurs in the vulvovaginal or inguinoscrotal regions and has no metastatic potential.
  • This tumor presents with slow clinical progression.

Purpose of the Study:

  • To report a rare case of cellular angiofibroma originating in the prostate.
  • To describe the clinical, histopathological, and molecular features of this unusual presentation.

Main Methods:

  • A 78-year-old man with obstructive lower urinary tract symptoms underwent open retropubic prostatectomy.
  • Histopathological evaluation included routine staining and immunohistochemistry.
  • Fluorescence in situ hybridization was performed for molecular analysis.

Main Results:

  • The prostate measured approximately 150 cc and showed a proliferation of spindle-shaped cells in a collagenous stroma with vascular proliferation.
  • Immunohistochemistry was positive for smooth muscle actin, desmin, and CD34, and negative for S100.
  • A deletion at chromosome 13q14 was identified.

Conclusions:

  • The findings support the diagnosis of cellular angiofibroma of the prostate.
  • This represents a rare occurrence of cellular angiofibroma in this anatomical location.
  • Further research may be needed to understand the behavior and management of prostatic cellular angiofibroma.