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Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
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Projection-specific Routing of Odor Information in the Olfactory Cortex

Simon Daste1,2, Tuan H Pham1,2, Max Seppo1,2

  • 1Department of Neuroscience, Division of Biology and Medicine, Brown University, Providence, RI, USA.

Biorxiv : the Preprint Server for Biology
|December 31, 2025
PubMed
Summary

Information routing in the mammalian cortex is clarified. Feedback neurons (olfactory bulb-projecting) encode odor identity early, while feedforward neurons (medial prefrontal cortex-projecting) encode it later, showing distinct plasticity.

Keywords:
Sensory processingbehaviorcalcium imagingcortical neural circuitslearningolfaction

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