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Wide-Field Imaging of Retinal Vascular Macroaneurysm Associated With Retinal Racemose Hemangioma
Yamato Katsura1, Hisashi Fukuyama1, Fumi Gomi1
1Department of Ophthalmology, Hyogo Medical University, Nishinomiya, Japan, hyo-med.ac.jp.
Case Reports in Ophthalmological Medicine
|December 31, 2025
Summary
This case report highlights successful treatment for exudative retinal vascular macroaneurysm (RVM) linked to retinal racemose hemangioma (RRH). Combined therapy with intravitreal bevacizumab and photocoagulation improved vision, emphasizing the need for diligent follow-up.
Area of Science:
- Ophthalmology
- Vascular Medicine
- Retinal Imaging
Background:
- Retinal vascular macroaneurysm (RVM) can present with exudative complications.
- Retinal racemose hemangioma (RRH) is a rare congenital vascular anomaly.
- Co-occurrence of RVM and RRH poses diagnostic and therapeutic challenges.
Purpose of the Study:
- To report a case of exudative RVM associated with RRH.
- To describe the clinical presentation and management of this combined condition.
- To evaluate the efficacy of a specific treatment regimen.
Main Methods:
- Observational case report.
- Diagnosis confirmed through fundus examination and optical coherence tomography angiography (OCTA).
- Treatment involved intravitreal bevacizumab injections and retinal photocoagulation.
Main Results:
- A 40-year-old woman presented with visual field defects and exudative RVM with RRH.
- Subretinal hemorrhage led to decreased visual acuity (20/63).
- Combined treatment resulted in RVM resolution (confirmed by OCTA) and visual acuity improvement to 20/20.
Conclusions:
- Combined intravitreal bevacizumab and photocoagulation is effective for exudative RVM.
- Wide-field OCTA is crucial for assessing arteriovenous malformations and monitoring treatment outcomes.
- Long-term follow-up is essential due to the potential for RVM recurrence in association with RRH.

