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Fulminant Immune Checkpoint Inhibitor-Induced Myocarditis and Complete Heart Block in Advanced Melanoma: A Case

Bakr Alhayek1, Xiaowei Malone1, Muhammad Affan Rashid1

  • 1Internal Medicine, AdventHealth Tampa, Tampa, USA.

Cureus
|December 31, 2025
PubMed
Summary

Fulminant immune checkpoint inhibitor-associated myocarditis can be fatal. Early recognition and aggressive immunosuppression, including second-line therapies, are crucial for managing this serious complication.

Keywords:
autoimmune cardiotoxicitycomplete heart blockfulminant myocarditisimmune checkpoint inhibitors (icis)immune-related adverse events (iraes)

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