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Updated: Jul 15, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Regenerative Approach Using Intramarrow Penetration in the Management of Grade II Furcation Defect: A Case Report
Jignesh Tate1, Saudamini More2, Tejal Patil3
1Periodontology, Bharati Vidyapeeth Dental college and Hospital, Navi Mumbai, Mumbai, IND.
Abstract:
Intramarrow penetration (IMP), which involves the perforation of the cortical bone to access the bone marrow, is an effective and novel approach for treating advanced furcation defects. The present case report explores the use of a regenerative technique combining IMP and guided tissue regeneration (GTR) in treating a mandibular grade II furcation defect. A 47-year-old male patient presented with pain in the lower right back region of the jaw. Initial non-surgical therapy, followed by a regenerative procedure involving IMP, bone graft placement, and resorbable membrane coverage, was employed. At six months, clinical and radiographic findings revealed successful bone regeneration, with complete defect fill and periodontal health restoration. The GTR demonstrated promising results in this patient.

