Spinning-Induced Exertional Rhabdomyolysis Without Acute Kidney Injury

Rhabdomyolysis is a condition with a myriad of causes, including both traumatic and non-traumatic. Traumatic conditions are observed in crush injuries, compartment syndrome, and fractures, while non-traumatic rhabdomyolysis is commonly seen due to exertional heat stroke, extreme physical exercise, and dehydration. This case report explores two cases of extreme non-traumatic rhabdomyolysis caused by indoor cycling, also known as spinning. A common complication of severe rhabdomyolysis is acute kidney injury (AKI), which increases the risk of renal failure. Rapid interventions such as aggressive intravenous fluids are necessary to prevent kidney function loss. In this case report, two sisters, on two separate occasions, developed Creatine Kinase (CK) levels greater than 100,000 U/L. Recent literature indicates that patients with creatine kinase (CK) levels between 5000 and 10,000 U/L have an increased likelihood of developing acute kidney injury (AKI). However, in these patients, despite creatine kinase (CK) levels ten times greater, these patients demonstrated no signs of acute kidney injury (AKI). This case report aims to highlight the importance of timely treatment of exertional rhabdomyolysis. We also explore the possibility of a genetic predisposition that might increase the likelihood of acquiring this condition. Finally, given the rising cases of spinning-induced rhabdomyolysis, we also highlight preventative measures to prevent future occurrences.