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Updated: Jan 7, 2026

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool
Published on: May 27, 2016
Using mathematical approaches to answer complex biological questions: can exosomal miRnas predict cancer prognosis?
Olka Missaghi1, Leman Nur Nehri1, Sepehr Bakhshi2
1Department of Biological Sciences, Orta Dogu Teknik Universitesi, Ankara, Turkiye.
None:
Epithelial to mesenchymal transition (EMT) has been widely implicated in diverse cellular processes such as development, would healing, as well as in cancer metastasis and therapy resistance. Exosomes are nanosized vesicles that carry cellular products and are known to mediate cell-cell communication. We describe here how a systems biology approach relying on simple experimental data in combination with in silico tools and mathematical modeling can be used to understand complex biological phenomenon such as EMT.
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