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Lower Adherence to Vitamin D Prophylaxis in Families With Multiple Children
Martina Panicola1, Giulia Cereghetti2, Carlo Agostoni1,3
1Department of Clinical Sciences and Community Health, Università Degli Studi di Milano, Milan, Italy.
Acta Paediatrica (Oslo, Norway : 1992)
|December 31, 2025
Summary
Infants in families with multiple children showed lower adherence to vitamin D supplementation. This finding highlights the need for targeted support to ensure adequate vitamin D intake for all infants.
Area of Science:
- Pediatrics
- Public Health
- Nutritional Science
Background:
- Vitamin D supplementation is crucial for infant health.
- Factors influencing adherence to vitamin D prophylaxis require investigation.
Purpose of the Study:
- To examine the association between family composition and adherence to vitamin D supplementation in infants.
- To identify household factors impacting vitamin D prophylaxis adherence.
Main Methods:
- Cross-sectional survey of 241 caregivers of infants (4-12 months) in Milan, Italy.
- Data collected on demographics, health, vitamin D administration, and family characteristics.
- Multivariable logistic regression analyzed factors associated with poor adherence.
Main Results:
- Overall adherence to vitamin D supplements (≥4 times/week) was 85%.
- Good adherence was higher in single-child families (91%) vs. multi-child families (78%).
- Having siblings was significantly associated with poor adherence (OR 2.72, 95% CI 1.25-5.92).
Conclusions:
- Adherence to vitamin D prophylaxis was significantly lower in families with more than one child.
- Family size is a key factor influencing vitamin D supplementation adherence in infants.
- Findings can inform counseling and interventions to improve vitamin D adherence.
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