Global Burden of Spinal Cord Injuries Attributable to Falls and Road Traffic Injuries in Working-Age Individuals, 1990 to 2021, with Projections through 2040: An Age-Period-Cohort Analysis

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Summary

This summary is machine-generated.

Spinal cord injuries from road injuries declined, but fall-related injuries are rising, especially in males and middle-aged groups. Targeted prevention strategies are crucial to address these persistent burdens and reduce socioeconomic costs.

Area Of Science

  • Epidemiology
  • Public Health
  • Traumatology

Background

  • Spinal cord injury (SCI) from falls and road incidents significantly impacts working-age individuals.
  • Temporal and geographic patterns of SCI in this demographic are not well understood.

Purpose Of The Study

  • To analyze the global, regional, and national burden of SCI from falls (SCIF) and road injuries (SCIR) in working-age individuals (15-64 years) from 1990-2021.
  • To project future trends of SCIF and SCIR through 2040.

Main Methods

  • Utilized Global Burden of Disease (GBD) 2021 data.
  • Assessed age-standardized incidence, prevalence, and years lived with disability rates.
  • Quantified trends using average annual percentage change and projected future burdens with Bayesian age-period-cohort models.

Main Results

  • Global SCIR burden significantly declined from 1990-2021, while SCIF showed modest reductions or increases in some regions.
  • Males experienced higher burdens; SCIF increased with age, peaking at 60-64 years, whereas SCIR shifted to older age groups.
  • High-SDI regions saw declines in both, middle-SDI areas experienced SCIF increases, and low-SDI regions showed slight SCIF rises. Projections indicate a modest rise in SCIF and a decrease in SCIR by 2040.

Conclusions

  • SCIR burden has decreased substantially and is projected to continue declining.
  • Persistent or rising SCIF trends, male predominance, age shifts, and socioeconomic disparities necessitate urgent, tailored prevention strategies.
  • Enhanced road safety and occupational fall prevention are critical to reduce inequities and socioeconomic costs.