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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
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Position Paper: Artificial Intelligence in Medical Image Analysis: Advances, Clinical Translation, and Emerging

A S Panayides, H Chen, N D Filipovic

    IEEE Journal of Biomedical and Health Informatics
    |December 31, 2025
    PubMed
    Summary

    Artificial intelligence (AI) advances, including hybrid CNN-Transformer models and foundation AI, are enhancing medical imaging analysis. These innovations facilitate clinical translation and integration into healthcare workflows, improving diagnostics and patient care.

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    Area of Science:

    • Medical Imaging and Artificial Intelligence
    • Clinical Translation of AI Technologies
    • Healthcare Workflow Integration

    Background:

    • AI adoption in medicine faces challenges.
    • Recent AI advancements offer solutions for medical applications.
    • The paper reviews AI progress in medical image and video analysis.

    Purpose of the Study:

    • To review recent advances in AI for medical imaging.
    • To outline emerging AI paradigms for healthcare.
    • To highlight pathways for successful clinical translation of AI.

    Main Methods:

    • Review of hybrid Convolutional Neural Network (CNN) Transformer architectures.
    • Application of foundation and generative AI models for transfer learning.
    • Implementation of federated learning for privacy-preserving collaboration.
    • Adoption of explainable and trustworthy AI approaches.

    Main Results:

    • State-of-the-art results in segmentation, classification, reconstruction, synthesis, and registration.
    • Enabling transfer learning for smaller datasets with limited ground truth.
    • Supporting privacy-preserving multi-institutional collaboration.
    • Fostering clinician trust and regulatory compliance through explainable AI.

    Conclusions:

    • AI developments are paving the way for integration into radiology, pathology, and healthcare.
    • Hybrid CNN-Transformer models show significant promise.
    • Foundation models and federated learning address key adoption barriers.
    • Explainable AI is crucial for ethical and trusted deployment.