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Performance of artificial intelligence in breast cancer screening programmes: a systematic review
Ghufran Jassim1, Osamah Otoom2, Bindhu Nair3
1Royal College of Surgeons in Ireland and Medical University of Bahrain, Muharraq, Busaiteen, Bahrain gjassim@rcsi-mub.com.
BMJ Open
|December 31, 2025
Summary
Artificial intelligence (AI) in breast cancer screening shows comparable diagnostic performance to radiologists and can significantly reduce workload, especially as a second reader or triage tool. Further research is needed for standalone AI use.
Area of Science:
- Radiology
- Artificial Intelligence
- Medical Imaging
- Oncology
Background:
- Growing interest in artificial intelligence (AI) for population breast cancer screening.
- Rapid expansion of evidence regarding AI applications in mammography.
Conclusions:
- Contemporary AI systems demonstrate diagnostic performance comparable to radiologists.
- AI can substantially reduce reading workload, particularly as a second reader or triage tool.
- Prospective evidence supports safe integration of AI in these roles; further long-term studies are needed for standalone use.

