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Cutaneous curiosity: axillary apocrine carcinoma
Harpyar Singh1, Raj K Chejara2, Lirangla Sangtam2
1General surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India harpyarsinghratia@gmail.com.
This case study presents a rare primary cutaneous apocrine carcinoma in a middle-aged male. Aggressive multimodal treatment, including surgery and radiotherapy, led to a recurrence-free outcome at six months.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Primary cutaneous apocrine carcinoma is a rare malignancy.
- Diagnosis can be challenging due to its rarity and presentation.
- Early detection and treatment are crucial for patient outcomes.
Purpose of the Study:
- To report a case of primary cutaneous apocrine carcinoma in a middle-aged male.
- To highlight diagnostic challenges and the importance of immunohistochemistry (IHC).
- To emphasize the role of multimodal treatment in achieving favorable outcomes.
Main Methods:
- Case presentation of a middle-aged male with an axillary mass.
- Diagnostic workup included MRI, biopsy, and immunohistochemistry (IHC).
- Treatment involved wide local excision, lymph node dissection, flap reconstruction, and radiotherapy.
Main Results:
- Biopsy and IHC confirmed primary cutaneous apocrine carcinoma.
- Tumor cells were positive for androgen receptor, oestrogen receptor, progesterone receptor, and GATA-3.
- The patient remained recurrence-free at 6 months post-treatment.
Conclusions:
- Thorough IHC is essential for diagnosing cutaneous apocrine carcinoma.
- Aggressive multimodal treatment is vital for managing this rare cancer.
- Prompt diagnosis and treatment can lead to favorable outcomes in patients.
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