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Multidimensional predictors of fatigue in amyotrophic lateral sclerosis: a cross-sectional study in China

Fangfang Cai1,2,3,4, Dandan Xu1,2,5,3,4, Dan Yang1,2,3,4

  • 1Motor Neuron Center, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.

Scientific Reports
|December 31, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Amyotrophic lateral sclerosisDepressionFatiguePredictorsSleepSocial determinants

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Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
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