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Updated: May 1, 2026

Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients
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Case Report: Generalized lipodystrophy following immune-checkpoint inhibitor therapy.

Andrew-Hyun Lee1,2, Rina Hui2,3, Jenny E Gunton1,2,4

  • 1Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, NSW, Australia.

Frontiers in Endocrinology
|January 1, 2026
PubMed
Summary

Immune checkpoint inhibitors (ICI) can cause lipodystrophy, a rare fat loss condition. This case highlights a patient developing severe lipodystrophy after pembrolizumab treatment for breast cancer.

Keywords:
adiposecheckpoint inhibitor therapydiabetesimmunotherapylipodystrophy

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