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Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
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Marked Sinus Bradycardia in a COVID-19 Patient

Carlos Valladares1, Adam Kaplan1

  • 1Department of Internal Medicine, Rutgers Health-Community Medical Center, Toms River, New Jersey, USA.

Case Reports in Cardiology
|January 1, 2026
PubMed

Insights

Coronavirus disease 2019 (COVID-19) can cause cardiac issues like sinus bradycardia, even in asymptomatic individuals. This case highlights the importance of monitoring heart rhythms in COVID-19 patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Cardiac manifestations, including bradycardia, are recognized complications of coronavirus disease 2019 (COVID-19).
  • Sinus node dysfunction can lead to bradycardia, a slower than normal heart rate.

Purpose of the Study:

  • To report a case of sinus bradycardia in an asymptomatic patient with COVID-19.
  • To emphasize the need for cardiac monitoring in COVID-19 patients.

Main Methods:

  • Case report of an unvaccinated 33-year-old female hospitalized with bradycardia.
  • Electrocardiogram (ECG) monitoring revealed significant heart rate reduction.
  • Exclusion of secondary causes of bradycardia through laboratory work-up and echocardiography.

Main Results:

  • The patient presented with symptoms of lightheadedness and dizziness.
  • Sinus bradycardia was observed, with heart rate dropping to 35/min.
  • No other secondary causes for bradycardia were identified.

Conclusions:

  • Baseline ECG monitoring is recommended for all hospitalized COVID-19 patients.
  • Vigilance for cardiac rhythm abnormalities is crucial for managing COVID-19 complications.
  • Further investigation is needed regarding physician response to marked bradycardia in COVID-19.
Abstract

Keywords:
COVID-19SARS-CoV-2case reportheart ratesinus bradycardia

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