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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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CELMoD-antibody conjugates unlock a CD38 feedback loop in multiple myeloma

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No abstract available in PubMed .

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Cereblon E3 ligase modulatorsDegrader–antibody conjugateMolecular glueMultiple myelomaPositive feedbackTargeted protein degradation

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