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Massive Pheochromocytomatosis Treated With Cytoreductive Surgery
Tobias Carling1,2, Alejandra Kalik3, Meredith LaRue1,2
1Carling Adrenal Center, Tampa, FL 33615, USA.
JCEM Case Reports
|January 1, 2026
Summary
Extensive pheochromocytomatosis, a rare condition, was successfully treated with cytoreductive surgery. Lifelong biochemical surveillance is crucial for patients with this adrenal tumor disorder.
Area of Science:
- Endocrinology
- Surgical Oncology
- Genetics
Background:
- Recurrent symptoms of pheochromocytoma (palpitations, anxiety, diaphoresis) occurred 9 years post-adrenalectomy.
- Biochemical tests showed elevated metanephrines, and imaging revealed widespread intra-abdominal tumor deposits and a liver lesion.
- Genetic testing was negative for common pathogenic variants associated with pheochromocytoma.

