Building a healthcare data warehouse: considerations, opportunities, and challenges
Tamara Knezevic Ivanovski1,2, Sailish Honap3,4, Rade Matic5
1Department of Gastroenterology and Hepatology, University City Hospital Zvezdara, Belgrade, Serbia.
Frontiers in Digital Health
|January 1, 2026
Summary
Healthcare data warehouses (DWs) are crucial for data-driven care, enabling better clinical decisions and research. Implementing effective DWs supports personalized, high-quality healthcare in the digital age.
Area of Science:
- Health Informatics
- Data Science in Healthcare
- Digital Health Transformation
Background:
- Digitalization is transforming healthcare towards data-driven, evidence-based practices.
- Healthcare data warehouses (DWs) are central to this transformation, aggregating and analyzing diverse clinical and administrative data.
- Effective DWs improve clinical decision-making, care quality, and research capabilities.
Purpose of the Study:
- To review the literature on building and implementing healthcare data warehouses.
- To introduce real-world, disease-specific applications of data warehousing in healthcare.
- To demonstrate adapting traditional DW design for national-scale digital health infrastructures, exemplified by BiotherDW.
Main Methods:
- Literature review of existing data warehouse development and implementation processes.
- Analysis of theoretical frameworks and practical healthcare applications.
- Case study of BiotherDW for national-scale digital health infrastructure.
Main Results:
- DWs provide timely access to comprehensive patient data for clinicians, enhancing decision-making and care quality.
- DWs facilitate population-level analytics, predictive modeling, and health service research for insights into disease patterns and system efficiencies.
- Successful DW implementation requires careful consideration of system architecture, data governance, interoperability, and ETL/ELT frameworks.
Conclusions:
- Data warehouses are essential infrastructure for personalized, high-quality, and cost-effective healthcare.
- DWs drive scalable research, operational efficiency, and evidence-based health policy.
- Adapting DW design, like with BiotherDW, is key for national digital health infrastructures.
Keywords:
ETL/ELTartificial intelligence in healthcaredata integration and interoperabilitydata warehourseinflammatory bowel diseaseMore Related Videos
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