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Updated: Jan 7, 2026

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High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
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Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning
Mojtaba Safari1, Shansong Wang1, Vanessa L Wildman1
1Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Arxiv
|January 2, 2026
Summary
This study introduces an efficient deep learning framework for Magnetic Resonance Imaging (MRI) super-resolution (SR), significantly improving anatomical detail and diagnostic accuracy. The novel approach balances high fidelity with computational efficiency, paving the way for clinical integration.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Biomedical Engineering
Background:
- High-resolution Magnetic Resonance Imaging (MRI) is crucial for diagnostics but limited by long acquisition times.
- Deep learning-based super-resolution (SR) methods offer potential but often involve a trade-off between image fidelity and computational efficiency.
Purpose of the Study:
- To develop a computationally efficient and accurate deep learning framework for MRI SR.
- The framework aims to preserve anatomical detail for seamless clinical integration.
Main Methods:
- A novel SR framework integrating multi-head selective state-space models (MHSSM) with a lightweight channel MLP was proposed.
- The model employed 2D patch extraction and hybrid scanning for long-range dependency capture, utilizing MambaFormer blocks with MHSSM, depthwise convolutions, and gated channel mixing.
- Evaluations were conducted on 7T brain T1 MP2RAGE and 1.5T prostate T2w MRI datasets, comparing against Bicubic, GANs, transformers, Mamba, and diffusion models.
Main Results:
- The proposed framework demonstrated superior performance and exceptional efficiency across both brain and prostate datasets.
- Achieved high SSIM and PSNR values (e.g., 0.951 SSIM, 26.90 dB PSNR for brain data), significantly outperforming all compared baselines (p<0.001).
- Required only 0.9M parameters and 57 GFLOPs, representing a 99.8% reduction in parameters and 97.5% reduction in computation compared to Res-SRDiff, while surpassing SwinIR and MambaIR in accuracy and efficiency.
Conclusions:
- The developed framework offers an efficient and accurate solution for MRI SR, enhancing anatomical detail in diverse datasets.
- Its low computational requirements and state-of-the-art performance indicate strong potential for clinical translation and adoption.
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