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Development and Validation of the Clinical Risk Prediction Model for Disseminated Intravascular Coagulation after
P V Skakun1,2, S A Alekseev3, A Ch Chasnoits1
1Department of Plastic Surgery and Combustiology, Institute of Qualification Improvement and Retraining, Belarusian State Medical University, Minsk, Republic of Belarus.
Annals of Burns and Fire Disasters
|January 2, 2026
Summary
Severe burn injuries can lead to disseminated intravascular coagulation (DIC), a condition linked to mortality. This study aims to develop a simple method for early DIC prediction in burn patients to improve outcomes.
Area of Science:
- Trauma surgery
- Hematology
- Critical care medicine
Background:
- Severe burns are a leading cause of death with significant socioeconomic impact.
- Disseminated intravascular coagulation (DIC) is a common and life-threatening complication in burn patients.
- Coagulopathy in burn survivors indicates mortality risk and influences treatment decisions.
Purpose of the Study:
- To develop a simple and effective approach for the early prediction of DIC syndrome post-severe burn injury.
- To identify high-risk patient groups for DIC.
- To facilitate timely preventive measures and treatment adjustments for DIC in burn victims.
Main Methods:
- The study focuses on developing a novel predictive model for DIC.
- The model aims to be simple, utilizing universally available markers.
- It will consider the specific pathophysiology of severe burn injuries.
Main Results:
- The study is designed to establish a new predictive model.
- Results will focus on the model's simplicity and effectiveness in early DIC detection.
- Validation of the model in identifying at-risk burn patients is anticipated.
Conclusions:
- Early prediction of DIC in severe burn patients is critical for improving survival rates.
- A simple and accessible predictive tool can aid in risk stratification and timely intervention.
- This approach may enhance the management of burn-induced coagulopathy.
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