Development and Validation of the Clinical Risk Prediction Model for Disseminated Intravascular Coagulation after...

Thermal trauma ranks among the top external causes of death and carries substantial socioeconomic impacts across all demographics. A prevalent complication following severe burn injuries is disseminated intravascular coagulation (DIC) syndrome. The onset of coagulopathy in severely burned patients is an early indicator of mortality risk, which persists throughout their clinical recovery. Early identification of DIC is crucial for determining the scope of surgical interventions. Concurrently, DIC presents a potential target for therapeutic intervention. Thus, forecasting the onset of DIC in burn victims, along with the capacity for its timely prevention and necessary treatment adjustments, is a critical objective. Current predictive models are complex and rely on specific markers not universally available in primary care settings for burn victims, nor do they consider the unique pathophysiological characteristics of severe burn injuries. Considering these factors, the purpose of this study is to develop a simple and effective approach to early prediction of DIC syndrome after severe burn injury in order to identify risk groups and initiate preventive measures.