Endo-hepatology: Bridging the gap between lumen and liver

In recent years, hepatology has undergone a transformative evolution driven by significant advancements in diagnostic and therapeutic technologies. The expanding integration of endoscopic modalities into hepatology has enforced the diagnosis, staging, management of liver diseases beside integration into transplantation. This review highlights the evolving discipline of "endo-hepatology", where endoscopic ultrasound, endoscopic retrograde cholangiopancreatography, and novel interventional tools are employed to address the critical challenges in chronic liver disease. The review provides a comprehensive synthesis of current evidence and different clinical applications, while also exploring future directions including revolution of artificial intelligence-assisted endoscopies and enhanced imaging endoscopies. By bridging the anatomical and functional interface between the gastrointestinal lumen and the liver, endo-hepatology is not only improving diagnostic accuracy and therapeutic precision but also reshaping multidisciplinary paradigms in hepatology practice.