Evaluating Creatinine and Urea Levels as a Predictor of Renal Failure in Burn Patients

Renal failure frequently occurs as the primary organ failure in patients with severe burns, but accurately defining acute kidney injury and renal failure remains complex. This study aims to explore the relationship between these commonly measured renal biomarkers, diuresis and clinical outcomes in burn patients. The purpose of this study was to investigate the relationship between serum creatinine and urea levels, and the clinical outcomes in burn patients. By analyzing this relationship, the study aims to enhance the understanding of renal function and its impact on prognosis in patients with severe burns, thereby improving the management and treatment strategies for this vulnerable patient population. This was a retrospective cohort study that examined patients from the Department of Burns and Plastic Surgery at "Mother Teresa" University Hospital Center in Tirana, Albania. Data were collected from the burn registry and Medical Records from January 2023 to April 2024. Elevated creatinine levels upon admission are linked with a higher risk of morbidity and mortality. Similarly, increased urea levels and low diuresis are also associated with poor prognosis in burn patients. We propose that both admission creatinine and urea levels, along with diuresis measurements, can serve as "warning signs" to identify patients at higher risk for adverse outcomes.