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Updated: Jan 7, 2026
05:12
Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Published on: September 4, 2017
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Developmental venous anomalies and cerebral cavernous malformations: Partners in crime
Nikolaos-Achilleas Arkoudis1,2, Manos Siderakis3, Ilianna Tsetsou4
1Research Unit of Radiology and Medical Imaging, National and Kapodistrian University of Athens, Athens 11528, Greece.
World Journal of Radiology
|January 2, 2026
Summary
Developmental venous anomalies (DVAs) and cerebral cavernous malformations (CMs) can coexist. Recognizing this association is crucial for diagnosing brain bleeds and managing these vascular lesions effectively.
Area of Science:
- Neurology
- Vascular Malformations
- Neuroimaging
Background:
- Developmental venous anomalies (DVAs) are congenital vascular malformations.
- Cerebral cavernous malformations (CMs) are vascular lesions prone to hemorrhage.
- Coexistence of DVAs and CMs can alter venous pressure and promote CM rupture.
Purpose of the Study:
- To review the imaging features of DVAs and CMs.
- To explore the clinical implications of coexisting DVAs and CMs.
- To emphasize the diagnostic importance of recognizing the DVA-CM association.
Main Methods:
- Literature review focusing on imaging characteristics.
- Analysis of clinical consequences in mixed lesions.
- Emphasis on diagnostic clues for occult CMs.
Main Results:
- DVAs and CMs exhibit distinct imaging appearances.
- Combined lesions can lead to increased risk of hemorrhage.
- A DVA adjacent to unexplained hemorrhage suggests an occult CM.
Conclusions:
- Recognizing the coexistence of DVAs and CMs is vital.
- This association aids in diagnosing intracerebral hemorrhage.
- Accurate diagnosis facilitates targeted patient management.
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