Correlation of 3D Echocardiography With Cardiac MRI in Patients With Acute Left Ventricular Dysfunction in the Age Group of One Month to 18 Years
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View abstract on PubMed
Summary
This summary is machine-generated.Three-dimensional echocardiography (3D-ECHO) strongly correlates with cardiac magnetic resonance imaging (CMR) for assessing left ventricular ejection fraction (LVEF) in children with acute left ventricular dysfunction. However, 3D-ECHO underestimates volumes, reinforcing CMR
Area Of Science
- Pediatric Cardiology
- Cardiovascular Imaging
- Medical Diagnostics
Background
- Acute left ventricular (LV) dysfunction in children requires accurate volumetric and functional assessment.
- Cardiac magnetic resonance imaging (CMR) is the gold standard for LV volume and function, but it is not always readily available.
- Three-dimensional echocardiography (3D-ECHO) offers a potential bedside alternative for evaluating LV function.
Purpose Of The Study
- To evaluate the correlation and agreement between 3D-ECHO and CMR in children with acute LV dysfunction.
- To assess end-diastolic volume (EDV), end-systolic volume (ESV), and left ventricular ejection fraction (LVEF) using both modalities.
- To identify systematic measurement errors between 3D-ECHO and CMR.
Main Methods
- An observational cohort study included 16 children (1 month to 18 years) with acute myocarditis or new-onset LV dysfunction.
- Data collected included clinical details, laboratory parameters, 3D-ECHO, and CMR findings.
- Pearson's correlation coefficient and Bland-Altman plots were used to analyze data.
Main Results
- A very strong positive correlation was observed between 3D-ECHO and CMR for LVEF (r=0.887), EDV (r=0.906), and ESV (r=0.903).
- 3D-ECHO consistently underestimated EDV (mean difference -18.86) and ESV (mean difference -21.77) compared to CMR.
- LVEF showed good agreement between 3D-ECHO and CMR (p=0.619).
Conclusions
- 3D-ECHO demonstrates strong correlation with CMR for LVEF assessment in pediatric acute LV dysfunction.
- 3D-ECHO can serve as a reliable bedside tool for evaluating systolic function in these children.
- Despite strong correlation for LVEF, the underestimation of EDV and ESV by 3D-ECHO confirms CMR's role as the gold standard for precise volumetric assessment.
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