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Updated: Jan 7, 2026

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Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
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Intraplacental Mature Cystic Teratoma
Audrey Brecher1, Alicia Vagnozzi2, Louis P Dehner2
1Saint Louis University School of Medicine, St. Louis, MO, USA.
Fetal and Pediatric Pathology
|January 2, 2026
Summary
Placental teratomas are rare benign tumors in singleton pregnancies. Accurate diagnosis is key to differentiate them from other conditions, preventing unnecessary interventions.
Area of Science:
- Obstetrics and Gynecology
- Pathology
- Reproductive Medicine
Background:
- Placental teratomas are benign germ cell tumors.
- They are composed of mature tissues from multiple germ layers.
- These tumors can mimic a cardiac fetus but lack organized fetal structures and an umbilical cord.
Purpose of the Study:
- To present a case of placental teratoma.
- To highlight diagnostic criteria and differentiation from other placental abnormalities.
- To emphasize the benign nature and lack of recurrence risk.
Main Methods:
- Case presentation of a singleton pregnancy with placental teratoma.
- Gross and histological examination of the placenta.
- Differential diagnosis discussion including acardiac twin and TRAP sequence.
Main Results:
- A 3.5 cm intraplacental lesion was identified.
- Histology confirmed mature tissues consistent with a mature cystic teratoma.
- The lesion lacked an umbilical cord and organized fetal structures.
Conclusions:
- Placental teratomas are distinct from acardiac twins and TRAP sequence.
- They occur in singleton pregnancies and have no recurrence risk.
- Accurate diagnosis is crucial to avoid misclassification and unnecessary interventions.
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