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Cerebral Metastasis From Recurrent Atrial Myxoma: A Case Report.
Obada Kholoki1, Ali Al Dailaty1, Johnny Atallah1
1Department of Internal Medicine, University of Connecticut, Farmington, CT, USA.
The American Journal of Case Reports
|January 2, 2026
Summary
Atrial myxomas, rare benign heart tumors, can recur and metastasize to the brain. This case highlights delayed recurrence and cerebral metastasis, emphasizing the need for lifelong patient surveillance.
Area of Science:
- Cardiology
- Neurology
- Oncology
Background:
- Atrial myxomas are benign cardiac tumors with potential for embolization and severe complications.
- Recurrence and distant metastasis of atrial myxomas are exceptionally rare events.
Purpose of the Study:
- To report a unique case of a young patient experiencing both late recurrence and cerebral metastasis of an atrial myxoma.
- To underscore the importance of long-term surveillance for atrial myxoma patients.
Main Methods:
- Case report of a 33-year-old male with a history of left atrial myxoma resection.
- Utilized brain imaging (MRI) and echocardiography to diagnose and monitor the condition.
- Involved surgical resection and gamma knife radiosurgery for metastatic lesions.
Main Results:
- The patient presented with ischemic strokes, later confirmed to be due to recurrent left atrial myxoma.
- Subsequent development of neurological symptoms led to the diagnosis of cerebral metastasis.
- Pathological examination confirmed myxomatous origin of the brain lesions.
Conclusions:
- This case illustrates two rare complications of atrial myxoma: delayed recurrence and central nervous system metastasis.
- Highlights the necessity for extended patient monitoring, even after decades post-initial resection.
- Emphasizes considering CNS metastatic disease in patients with neurological symptoms and a history of cardiac myxoma.
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