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Clinical analysis of 255 children with multiple serous effusions
Wenwen Jin1, Liying Lu1, Qiqi Gao1
1The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Pediatric multiple serous effusions stem from diverse causes like pneumonia and trauma, varying with age and sex. The number of affected cavities indicates disease severity, guiding clinical decisions.
Area of Science:
- Pediatric Medicine
- Clinical Pathology
- Medical Research
Background:
- Multiple serous effusions in children present a complex diagnostic challenge.
- Understanding the etiological spectrum and clinical features is crucial for effective management.
- This study investigates the causes and characteristics of multiple serous effusions in pediatric patients.
Purpose of the Study:
- To analyze the etiological spectrum of multiple serous effusions in pediatric patients.
- To correlate clinical features and pathological findings with effusion characteristics.
- To inform clinical decision-making for pediatric patients with multiple serous effusions.
Main Methods:
- A retrospective study was conducted on 255 pediatric patients.
- Data were collected from January 1, 2014, to July 1, 2024.
- Etiologies, clinical features, and effusion characteristics were analyzed.
Main Results:
- Pneumonia (31.37%) and trauma (10.98%) were the most common causes.
- Etiologies showed age and sex-specific patterns, with distinct patterns for tumors and connective tissue diseases.
- Pleural effusion was most common (95.3%), followed by peritoneal (73.3%) and pericardial (53.3%).
- Effusion characteristics correlated with underlying diseases; triple cavity effusions indicated more severe disease with specific biomarker changes.
Conclusions:
- The etiology of pediatric multiple serous effusions is diverse and age-dependent.
- Effusion location and characteristics are linked to the underlying cause.
- The extent of effusion involvement may predict disease severity in pediatric patients.
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