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Periprosthetic Solitary Fibrous Tumor of the Proximal Femur: A Case Report
Dev Laungani1, Bhargavi Maheshwer2, Alessandra Nascimento3
1Case Western Reserve University School of Medicine, Cleveland, Ohio.
Case:
A 77-year-old man with myelodysplastic syndrome presented with a dedifferentiated solitary fibrous tumor (SFT) of the proximal femur in the setting of a prior total hip arthroplasty. Diagnosis involved biopsy, NAB2::STAT6 gene fusion identification, and imaging. Management included wide resection, revision arthroplasty, and postoperative infection control. Despite local control, metastatic lung disease developed, and the patient opted for hospice care.
Conclusion:
This case underscores the aggressive potential of dedifferentiated SFTs and highlights the diagnostic role of NAB2::STAT6 fusion. It emphasizes the importance of multidisciplinary care in managing rare, high-risk tumors of the bone.
