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Short-Term Perfluoro-N-Octane Tamponade for Combined Penetrating Keratoplasty and Pars Plana Vitrectomy
Tomoki Kurihara1,2,3, Hiroshi Eguchi1, Fumika Hotta1
1Department of Ophthalmology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.
Purpose:
To report the efficacy of short-term perfluoro-n-octane (PFO) tamponade in combined penetrating keratoplasty and pars plana vitrectomy (PPV) for eyes with corneal pathology and proliferative vitreoretinopathy.
Methods:
Six consecutive patients with corneal pathology and proliferative vitreoretinopathy underwent PPV using a temporary keratoprosthesis and short-term PFO tamponade. Penetrating keratoplasty was performed with PFO retained in the vitreous cavity either during the initial surgery or at a secondary procedure, depending on graft availability.
Results:
Complete retinal reattachment was achieved in all six eyes (100%) at the final visit, including three eyes that required persistent silicone oil (SO) tamponade. Visual acuity improved in four eyes (67%) and decreased in two eyes (33%). Hypotony (<5 mmHg) was observed in four eyes preoperatively and five eyes postoperatively. Corneal graft failure occurred in one eye during a mean follow-up period of 34.5 (range: 10-83) months. Retaining PFO in the vitreous cavity, compared with SO or fluid, seemed effective in stabilizing the globe and facilitating cornea graft sutures.
Conclusion:
Short-term PFO tamponade for combined penetrating keratoplasty and PPV may be a useful surgical approach for cases involving corneal pathology and proliferative vitreoretinopathy.
