A Primary Pulmonary Primitive Neuroectodermal Tumor Invading the Left Atrium Through the Right Inferior Pulmonary...

Area of Science:

• Oncology
• Cardiology
• Pulmonology

Background:

• Primitive neuroectodermal tumors (PNETs) are aggressive neoplasms rarely found in the lungs.
• Primary pulmonary PNET invading the left atrium is an exceptionally rare clinical presentation.

Purpose of the Study:

• To report a unique case of primary pulmonary PNET with left atrial invasion in a pediatric patient.
• To describe the diagnostic and therapeutic approach for this rare condition.

Main Methods:

• Contrast-enhanced CT and PET-CT for tumor visualization.
• Transthoracic echocardiography for assessing cardiac involvement.
• Needle biopsy for histopathological diagnosis.
• Combination chemotherapy followed by surgical resection.

Main Results:

• A 12-year-old girl presented with symptoms suggestive of a lung mass.
• Imaging confirmed a primary pulmonary PNET invading the left atrium via the right inferior pulmonary vein.
• Multimodal treatment including chemotherapy and surgery led to tumor size reduction and resection.
• The patient remained disease-free five years post-treatment.

Conclusions:

• Primary pulmonary PNET with left atrial invasion is a rare but treatable condition.
• A multidisciplinary approach combining advanced imaging, chemotherapy, and surgery is crucial for successful management.
• Long-term surveillance is essential for patients with PNET.