Related Experiment Video

Updated: Jan 7, 2026

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells
06:39

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells

Published on: April 21, 2022

3.4K

Discovery of thiadiazole-based small-molecule inhibitors of SARS-CoV-2 spike-ACE2 interaction through integrated

Zakkia Gul1, Syed Ahsan Shahid2,3, Obaid-Ur-Rahman Abid4

  • 1Department of Biotechnology and Genetic Engineering, Hazara University, Mansehra, 21300, Pakistan.

Scientific Reports
|January 3, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
ACE2 interactionAntiviral developmentSARS-CoV-2 spike proteinSmall-molecule inhibitorsThiadiazole derivatives

More Related Videos

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

2.7K
Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
06:03

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16

Published on: July 15, 2019

8.3K

Related Experiment Videos

Last Updated: Jan 7, 2026

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells
06:39

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells

Published on: April 21, 2022

3.4K
Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

2.7K
Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
06:03

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16

Published on: July 15, 2019

8.3K

Related Concept Videos

Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

1.6K
Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
1.6K

Articles linked to this work by shared authors, journal, and citation graph.

Potential role of Adansonia digitata nanoparticles on colorectal cancer induced by colorectal cancer cells (SW620) in nude mice.

Journal, genetic engineering & biotechnology·2026

Integrated Network Pharmacology and Molecular Docking Uncover Multi-Target Actions of Cladophora glomerata-Derived Compounds Against Chronic Obstructive Pulmonary Disease.

International journal of molecular sciences·2026

Fabrication and structural analysis of CuO-NiO and MWCNTs@CuO-NiO hybrid nanostructures: versatile materials for environmental and biomedical remediation.

RSC advances·2025

Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women.

Saudi medical journal·2025

Degradation of polyvinyl chloride (PVC) microplastics employing the actinobacterial strain Streptomyces gobitricini.

Biodegradation·2025

Nutritional Innovation Using Green Seaweed (Ulva sp.) and Garlic Powder Extracts for White-Leg Shrimp (Litopenaeus vannamei) Challenged by Vibrio harveyi.

Veterinary medicine and science·2024

Searching for separation between frequency-modulated calls of blue and fin whales.

Scientific reports·2026

Isolation and characterization of plant plasma membrane P-type H+-ATPase dimers.

Scientific reports·2026

Cold-induced vasomotion changes in healthy individuals and patients after median or ulnar nerve repair.

Scientific reports·2026

Integrated expression profiling reveals molecular crosstalk between CFTR, FASN, FRAP (mTOR), and BANK1 in hepatocellular carcinoma.

Scientific reports·2026

Low-cost IoT real-time environmental monitoring and one-hour LSTM forecasting for small-scale agricultural applications.

Scientific reports·2026

Emotion regulation strategy use and daily levels of affective arousal, affective valence and dissociation in a clinical sample.

Scientific reports·2026

Anti-Inflammatory Activity of Cotula cinerea Essential Oil: Integrated Chemical, In Vivo, Histological, and Computational Evaluation.

Chemistry & biodiversity·2026

Computational drug design, synthesis, acetylcholinesterase inhibition and kinetic evaluation of novel benzothiazole-thiadiazole/oxadiazole derivatives.

Future medicinal chemistry·2026

Discovery of PIM-1 kinase inhibitors from marine natural products through machine learning and structure-based screening.

Research in pharmaceutical sciences·2026

Synthesis, in vitro and in silico evaluation of quinazoline and triazoloquinazoline derivatives as PDE7A inhibitors.

Research in pharmaceutical sciences·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us