Analysis of Clinical Efficacy of Surgical Progressive Treatment for Corrosive Esophageal Stricture in Children
View abstract on PubMed
Summary
This summary is machine-generated.Progressive, individualized surgical treatments effectively manage corrosive esophageal stricture in children. These methods, including balloon dilation and esophageal reconstruction, show promising clinical outcomes for pediatric patients.
Area Of Science
- Pediatric Surgery
- Gastroenterology
- Otolaryngology
Background
- Corrosive esophageal stricture poses a significant challenge in pediatric care.
- Ingestion of acidic substances, alkaline substances, and button batteries are common causes.
- Timely and effective intervention is crucial to prevent long-term complications.
Purpose Of The Study
- To evaluate the clinical efficacy of a progressive, individualized surgical treatment strategy for pediatric corrosive esophageal stricture.
- To assess the outcomes of sequential interventions including balloon dilation, Mitomycin C injection, stent placement, and reconstruction.
- To determine the safety and feasibility of these progressive treatment methods.
Main Methods
- Retrospective analysis of 52 children with corrosive esophageal stricture treated between January 2017 and December 2024.
- Application of sequential treatments: direct vision gastroscopic balloon dilation, balloon dilation with Mitomycin C, esophageal stent placement, and esophageal reconstruction.
- Evaluation of outcomes using esophagography, gastroscopy, and dysphagia grading, with statistical comparison via t-test or chi-square test.
Main Results
- All 52 pediatric patients were successfully discharged.
- Simple balloon dilation yielded good results in 22 cases.
- Combined balloon dilation with Mitomycin C and subsequent stent placement or reconstruction showed good outcomes in the majority of treated cases.
- Progressive treatment steps demonstrated increasing success rates with each intervention.
Conclusions
- Progressive, individualized surgical management is effective for pediatric corrosive esophageal stricture.
- The sequential approach involving balloon dilation, Mitomycin C, stent placement, and reconstruction offers a viable treatment pathway.
- These methods are characterized by simplicity, ease of operation, and promote positive clinical outcomes.
Related Concept Videos
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Cervical Esophageal Perforations: Symptoms may include neck pain, difficulty swallowing, painful...

