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Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
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Gold(I)-Catalyzed Synthesis of 1H‑Isochromenes

Julianna M Mouat1, Navraj Singh2, Miles L McCue2

  • 1Southwestern University, Department of Chemistry and Biochemistry, 1001 E. University Ave., Georgetown, Texas 78626, United States.

ACS Omega
|January 5, 2026
PubMed
Summary

A new gold-catalyzed reaction efficiently synthesizes valuable 1H-isochromenes from alkynylbenzyl alcohols. This atom-economical method provides high yields and excellent regioselectivity for medical applications.

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