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Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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Primary Angiosarcoma of Bone of the Skull Base: A Case Report and Literature Review

Muhammad Rashid Hanif1, Saif Ur Rab1, Nausheen Yaqoob2

  • 1Medical Oncology, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, OMN.

Cureus
|January 5, 2026
PubMed

Insights

Primary angiosarcoma of bone (PAB) is a rare and aggressive cancer. This study reviews PAB treatment options, highlighting limited evidence for systemic therapies and poor prognosis after relapse.

Area of Science:

  • Oncology
  • Bone Tumors
  • Sarcoma Research

Background:

  • Primary angiosarcoma of bone (PAB) is a rare malignancy with aggressive behavior.
  • Systemic relapse is frequent after surgical resection, leading to a poor prognosis.
  • Current evidence on systemic therapy efficacy for PAB is limited, based mainly on case reports and series.
Keywords:
aim chemotherapyepithelioid angiosarcomafdg-petpabpaclitaxel

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