Stress and Acute Coronary Syndrome
Shereif H Rezkalla1, Robert A Kloner2,3
1Marshfield Clinic Research Institute, Marshfield, WI, USA.
Cardiology Research
|January 5, 2026
Summary
Emotional stress, including from natural disasters and personal life events, can trigger acute cardiac events like myocardial infarction. Managing stress is crucial for patients with coronary artery disease.
Area of Science:
- Cardiology
- Psychosomatic Medicine
Background:
- Coronary atherosclerosis is driven by risk factors like hypercholesterolemia, smoking, and hypertension.
- Plaque rupture leads to myocardial infarction, but triggers of rupture, especially emotional stress, require more attention.
Purpose of the Study:
- To investigate the impact of emotional stress on triggering acute cardiac events.
- To highlight the role of emotional stress in myocardial infarction development.
Main Methods:
- Review of literature on emotional stress and acute cardiac events.
- Analysis of associations between natural disasters, life events, and myocardial infarction incidence.
Main Results:
- Severe emotional stress, from events like earthquakes or marital/work issues, significantly increases myocardial infarction occurrence.
- This effect is more pronounced in individuals with existing coronary artery disease or risk factors.
- Early morning severe events exacerbate cardiac risks.
Conclusions:
- Emotional stress is a significant trigger for acute cardiac events, particularly myocardial infarction.
- Stress management during hospitalization and rehabilitation for myocardial infarction is essential.
- Further attention to emotional stress triggers is needed in cardiovascular care.
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