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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Jan 7, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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Advancing Glaucoma Treatment through Materials Science: A Bibliometric Analysis.

Junran Li1, Huijie Hao1, Bo Yu1

  • 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

Journal of Current Ophthalmology
|January 5, 2026
PubMed
Summary

Materials science is advancing glaucoma treatment with new biomaterials and nanotechnologies. Research shows steady growth, with the United States leading in publications, focusing on innovative drug delivery and surgical materials for better patient outcomes.

Keywords:
BibliometricsGlaucomaHydrogelMaterialMicroinvasive glaucoma surgeryNanomaterialTreatment

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Ophthalmology

Background:

  • Glaucoma treatment is evolving with innovations in materials science.
  • Understanding research trends is crucial for developing advanced therapies.
  • Materials science offers potential for improved drug delivery and surgical interventions.

Purpose of the Study:

  • To identify recent research trends in advancing glaucoma treatment through materials science.
  • To analyze publications by country, institution, and author.
  • To focus on the impact of materials science on glaucoma therapy.

Main Methods:

  • Bibliometric analysis of 936 publications from January 1, 2015, to October 24, 2024.
  • Data sourced from the Web of Science Core Collection.
  • Visualization and trend analysis using Microsoft Excel and VOSviewer.

Main Results:

  • A steady increase in global publications on materials science for glaucoma treatment.
  • The United States, Egyptian Knowledge Bank, and Jui-Yang Lai identified as leading contributors.
  • Key research clusters include surgical materials, nanoparticle retinal protection, and advanced drug delivery systems.
  • Emerging hotspots include microshunts, Minimally Invasive Glaucoma Surgery (MIGS), and d-optimal design.

Conclusions:

  • Materials science advancements, including biomaterials and nanotechnology, are crucial for glaucoma treatment.
  • Innovations facilitate enhanced drug delivery, improved devices, and novel surgical materials.
  • These developments promise more effective, personalized, and minimally invasive therapies for glaucoma patients.