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Related Experiment Video

Updated: May 5, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
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Transient Changes in Wide-Field Choroidal Thickness after Photorefractive Keratectomy for Myopia: A Case-Control

Negareh Yazdani1,2, Hosein Hoseini-Yazdi3, Nasser Shoeibi4

  • 1Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.

Journal of Current Ophthalmology
|January 5, 2026
PubMed
Summary

Photorefractive keratectomy (PRK) in young myopes caused a temporary, small increase in choroidal thickness within one week post-surgery. This transient thickening resolved within six months, indicating no long-term changes in choroidal thickness after PRK.

Keywords:
ChoroidChoroidal thicknessMyopiaPhotorefractive keratectomy

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Retinal Imaging

Background:

  • Myopia affects a significant portion of the young adult population.
  • Photorefractive keratectomy (PRK) is a common refractive surgery for myopia correction.
  • Understanding the impact of PRK on ocular structures, including the choroid, is crucial for patient care.

Purpose of the Study:

  • To investigate longitudinal changes in choroidal thickness after photorefractive keratectomy (PRK) in young adult myopes.
  • To compare these changes with a control group of myopic individuals not undergoing PRK.

Main Methods:

  • 14 myopic subjects undergoing PRK and 13 controls were studied.
  • Choroidal thickness was measured at baseline and at 1 week, 1 month, 3 months, and 6 months post-PRK.
  • Linear mixed models analyzed changes over time and between groups.

Main Results:

  • A significant difference in longitudinal choroidal thickness changes was observed between groups (P < 0.001).
  • Choroidal thickness increased by 8 ± 3 μm one week post-PRK, significantly more than controls (-1 ± 3 μm; P = 0.04).
  • This thickening was transient, with no significant differences at 1, 3, or 6 months.

Conclusions:

  • Myopic PRK induces a small, transient, and uniform thickening of the choroid within one week.
  • This choroidal change is not sustained long-term, resolving by six months post-surgery.