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Related Concept Videos

Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Cognitive Development During Adulthood01:30

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Related Experiment Video

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Examining the Relationship Between Incarceration and Healthy Aging.

Elaine Eggleston Doherty1, Brittany A Bugbee1, Kerry M Green1

  • 1Department of Behavioral and Community Health, University of Maryland, 4200 Valley Drive, College Park, MD 20742 USA.

Journal of Developmental and Life-Course Criminology
|January 5, 2026
PubMed
Summary

Incarceration history is linked to poorer healthy aging outcomes, including physical and mental health, and functional abilities. Even early criminal legal system contact, like arrests, shows similar negative impacts on aging.

Keywords:
Criminal legal system contactHealthy agingLife courseLongitudinal

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Area of Science:

  • Public Health
  • Gerontology
  • Criminology

Background:

  • Collateral consequences of incarceration on health, aging, and mortality are increasingly understood.
  • Research is expanding on the long-term health impacts of the criminal legal system.

Purpose of the Study:

  • To examine the association between incarceration history and healthy aging in a Black community cohort.
  • To assess how criminal legal system contact impacts physical health, mental health, cognitive function, sleep, and hearing.

Main Methods:

  • Analysis of a community cohort of Black men and women followed from first grade (1966) to age 62.
  • Utilizing newly collected data on aging at age 62 and retrospective incarceration history.
  • Controlling for race, age, early life context, and early life variables.

Main Results:

  • Incarceration history is associated with significantly less healthy aging compared to never being arrested.
  • Detrimental effects on aging were observed across multiple indicators, including physical and mental health, and functional abilities.
  • Individuals with arrests but no incarceration experienced similar negative impacts on healthy aging.

Conclusions:

  • Criminal legal system contact, including incarceration and arrests, is linked to adverse healthy aging outcomes.
  • Findings highlight the need for a life course perspective on the health impacts of the criminal legal system.
  • This study provides a foundation for future research on criminal legal system contact and broadly defined healthy aging.