Basic Science and Pathogenesis.

Area of Science:

• Indigenous Health Research
• Dementia Studies
• Decolonization in Science

Background:

• Indigenous communities in Canada face higher dementia rates and advocate for decolonized research approaches.
• The Canadian Consortium of Neurodegenerative Aging (CCNA) has progressively supported Indigenous self-determination in dementia research over the last 10 years.

Purpose of the Study:

• To detail the evolution of Indigenous self-determination in dementia research within the CCNA framework.
• To outline strategies employed to strengthen Indigenous-led research capacity and promote culturally safe approaches.

Main Methods:

• Strengthened Indigenous-led research through a dedicated team and the Indigenous Cognitive Health Program.
• Facilitated knowledge sharing and capacity building via gatherings, webinars, and online platforms.
• Supported the development of Indigenous researchers, trainees, and community partnerships.

Main Results:

• Developed influential tools like the Canadian Indigenous Cognitive Assessment and assessed the Brain Health Pro platform.
• Expanded the Indigenous scientific team, submitted new funding proposals, and hosted educational webinars.
• Launched a website to guide culturally safe Indigenous health research practices.

Conclusions:

• Significant progress has been made in preparing Indigenous communities to address rising dementia prevalence.
• A future vision for a self-determined Community-Centred Indigenous Cognitive Health Network (CICHN) aims to sustain and build upon this increased capacity.