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FedGraphHE: A privacy-preserving federated graph neural network framework with dynamic homomorphic encryption and
Aocheng Zuo1, Zhanshen Feng2, Yuan Ping2
1School of Information and Control Engineering, Jilin University of Chemical Technology, Jilin, China.
Plos One
|January 6, 2026
Summary
Federated learning with graph neural networks (GNNs) enhances healthcare AI. FedGraphHE introduces a novel framework using homomorphic encryption to secure collaborative intelligence, improving accuracy and reducing costs while resisting attacks.
Area of Science:
- Artificial Intelligence
- Machine Learning
- Network Security
Background:
- Federated learning (FL) allows collaborative AI model training across devices without sharing raw data.
- Graph neural networks (GNNs) are effective for analyzing complex relationships in healthcare data.
- Existing federated GNNs struggle with privacy vulnerabilities, high computational costs, and Byzantine attacks.
Purpose of the Study:
- To develop FedGraphHE, a privacy-preserving federated GNN framework for secure collaborative intelligence in smart healthcare.
- To address gradient privacy, computational overhead, and Byzantine attack challenges in federated GNNs.
Main Methods:
- Integration of three synergistic modules: Dynamic Adaptive Partitioned Homomorphic Encryption (DAPHE) for optimized gradient transmission.
- Hierarchical Multi-scale Adaptive Graph Transformer (HMAGT) for encryption-aware graph processing.
- Federated Robust Aggregation via Homomorphic Inner Product (FRAHIP) for Byzantine-resilient aggregation.
Main Results:
- FedGraphHE outperforms existing privacy-preserving methods on citation network benchmarks (Cora, CiteSeer, PubMed).
- Achieved 98.18% classification accuracy on medical imaging datasets (ISIC 2020).
- Reduced communication costs by ~25% compared to homomorphic encryption baselines and maintained >95% accuracy under Byzantine attacks.
Conclusions:
- FedGraphHE offers an effective solution for privacy-sensitive collaborative learning in healthcare.
- The framework enhances diagnostic accuracy and security in smart healthcare networks.
- Demonstrates significant improvements in performance, efficiency, and robustness over existing methods.
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