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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Related Experiment Video

Updated: Jan 13, 2026

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
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Cost-Effectiveness of Thyroid Nodule Risk Stratification Guidelines.

Natalie Vankka1, Bo Bao2, Alexandria Webb3

  • 1Department of Radiology and Diagnostic Imaging, University of Alberta Faculty of Medicine and Dentistry.

Ultrasound Quarterly
|January 6, 2026
PubMed
Summary
This summary is machine-generated.

Adhering to American College of Radiology (ACR) TI-RADS and American Thyroid Association (ATA) guidelines for thyroid nodules can significantly reduce healthcare costs. The ACR TI-RADS approach is slightly more cost-effective, potentially saving up to $88,000 annually by reducing unnecessary biopsies.

Keywords:
ACR TI-RADSATAcost analysisthyroid cancerthyroid nodule

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Area of Science:

  • Radiology
  • Medical Economics
  • Endocrinology

Background:

  • Thyroid nodules are common, requiring accurate risk stratification for appropriate management.
  • Current guidelines, including ACR TI-RADS and ATA, aim to standardize thyroid nodule evaluation.
  • Variations in guideline adherence can impact healthcare resource utilization and costs.

Purpose of the Study:

  • To evaluate the potential cost savings associated with consistent adherence to the 2017 ACR TI-RADS and 2015 ATA guidelines for thyroid nodule assessment.
  • To compare the cost-effectiveness of ACR TI-RADS versus ATA criteria in managing thyroid nodules.

Main Methods:

  • Retrospective review of ultrasound features for 291 cytology-proven thyroid nodules.
  • Independent scoring of nodules by two radiologists using ACR TI-RADS and ATA guidelines.
  • Calculation and comparison of expected costs of guideline adherence versus actual healthcare system costs.

Main Results:

  • Strict adherence to either guideline could save the healthcare system up to $88,000 annually.
  • ACR TI-RADS recommended fewer fine-needle aspirations (147) compared to ATA (261), while recommending more follow-up ultrasounds (51 vs. 9).
  • ACR TI-RADS demonstrated slightly greater annual cost savings (approximately $3000) compared to ATA.

Conclusions:

  • Consistent application of ACR TI-RADS and ATA guidelines can lead to substantial cost savings by minimizing unnecessary thyroid biopsies.
  • The ACR TI-RADS guideline appears to be more cost-effective than the ATA guideline for thyroid nodule evaluation.