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Tailored Individual Follow-Ups Versus a One-Day Group Course in Patients With Long COVID (Post- COVID-19 Condition):
Marte Wilson1, Synne Garder Pedersen1,2, Nina Langeland3,4,5
1Department of Rehabilitation, University Hospital of North Norway, Tromsø, Norway.
JMIR Research Protocols
|January 6, 2026
Summary
This randomized controlled trial compares individualized rehabilitation to a group course for long COVID patients. Individualized care shows promise for improving quality of life and managing long COVID symptoms.
Area of Science:
- Rehabilitation Medicine
- Infectious Diseases
- Public Health
Background:
- Long COVID (post-COVID-19 condition) affects many individuals, impacting daily life, quality of life, and work capacity.
- The societal and economic burden of long COVID necessitates research into effective rehabilitation strategies.
- Existing research highlights the need for further investigation into the efficacy of rehabilitation services for long COVID patients.
Purpose of the Study:
- To evaluate the effectiveness of tailored individual follow-ups compared to a 1-day group course for patients with long COVID.
- To assess the feasibility and utility of a mobile application for self-monitoring goal achievement in long COVID rehabilitation.
- To provide evidence-based guidance for future long COVID treatment and rehabilitation protocols.
Main Methods:
- A single-center, parallel-group, superiority randomized controlled trial with 1:1 allocation.
- 62 outpatients aged 18-65 with long COVID were randomized to either individualized rehabilitation or a 1-day self-management group course.
- The primary outcome was the between-group difference in health-related quality of life (EQ-5D-5L index) at 6 months; secondary outcomes included symptom improvement, work participation, and neurocognitive function.
Main Results:
- Data enrollment began in October 2023, with 62 participants included by November 2024.
- Data collection is scheduled for completion in November 2025.
- This section will report on the primary and secondary outcomes comparing the two intervention groups.
Conclusions:
- Individualized outpatient rehabilitation programs offer potential benefits for long COVID patients.
- The study will inform treatment recommendations and improve long-term outcomes for individuals with long COVID.
- Findings will contribute knowledge on neuropsychological function and digital self-management tools in long COVID rehabilitation.
Keywords:
cognitive behavioral therapycognitive trainingexercisefatiguegraded activitymobile appspostacute COVID-19 syndromerandomized controlled trialrehabilitationtelerehabilitationMore Related Videos
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