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Related Experiment Video

Updated: Jan 13, 2026

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GaitDynamics: a generative foundation model for analyzing human walking and running.

Tian Tan1,2, Tom Van Wouwe3, Keenon F Werling4

  • 1Department of Bioengineering, Stanford University, Stanford, CA, USA. alanttan@stanford.edu.

Nature Biomedical Engineering
|January 6, 2026
PubMed
Summary
This summary is machine-generated.

We developed GaitDynamics, a novel deep learning model trained on diverse human gait data. This foundation model accurately predicts gait forces and motions, aiding mobility and injury prevention.

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Area of Science:

  • Biomechanics
  • Artificial Intelligence
  • Human Mobility

Background:

  • Understanding human gait dynamics (motion and forces) is crucial for mobility.
  • Existing deep learning models for gait analysis are limited by small, homogeneous datasets and single-output predictions.
  • Costly lab experiments and simulations are traditional methods for gait analysis.

Purpose of the Study:

  • To develop a versatile generative foundation model for human gait analysis.
  • To enable flexible inputs and outputs for diverse clinical applications.
  • To overcome limitations of existing deep learning models in gait research.

Main Methods:

  • Developed GaitDynamics, a generative foundation model.
  • Trained the model on a large, diverse dataset of human gait patterns.
  • Utilized deep learning for flexible input/output predictions.

Main Results:

  • GaitDynamics accurately estimates ground reaction forces from kinematics, even with missing data.
  • The model predicts the effects of gait modifications on knee loading without extensive experiments.
  • It predicts kinematic and force changes associated with varying running speeds.

Conclusions:

  • GaitDynamics demonstrates high accuracy and efficiency in gait analysis.
  • The model has potential for assessing and optimizing gait for injury prevention, disease treatment, and performance coaching.
  • Publicly shared data, code, and models facilitate further research and application.