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Updated: Jan 13, 2026

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Imaging pediatric osteomyelitis: The role of 99mTc-HDP bone scintigraphy and the additional value of SPECT/CT imaging

Saxby Brown1, Eva A Wegner1,2, Monica A Rossleigh1,2

  • 1Department of Nuclear Medicine, Prince of Wales and Sydney Children's Hospital, Barker Street, Randwick, NSW 2031, Australia.

Radiology Case Reports
|January 6, 2026
PubMed

Insights

Diagnosing pediatric osteomyelitis is difficult due to vague symptoms and normal labs. Triple-phase bone scintigraphy with SPECT/CT aids in accurate diagnosis and localization of osteomyelitis in children.

Area of Science:

  • Pediatric Radiology
  • Nuclear Medicine
  • Orthopedic Surgery

Background:

  • Pediatric osteomyelitis diagnosis presents challenges due to nonspecific symptoms and potentially normal early laboratory results.
  • Timely and precise diagnosis is crucial to avert long-term complications in children.
  • Magnetic resonance imaging (MRI) may be logistically difficult in pediatric cases requiring general anesthesia.

Keywords:
Bone scintigraphyLumbar spineOsteomyelitisPediatricSPECT/CTTalar bone

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